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IGKJ2::IGKC

High support

Canonical-transcript structure of the two partner genes, and the read-level evidence supporting the fusion in each tumor sample.

Known studies

No published studies in the Mitelman database describe the IGKJ2::IGKC gene fusion. It may be novel, private to this case, or a technical artifact — absence from a curated database is not by itself evidence either way.

Canonical transcripts in genomic order spliced together in the fusion mRNA 3.8 kb apart chr2 IGKC (-) ENST00000390237 · Ensembl canonical 88,857,683 breakpoint 88,857,161 88,857,683 1 exons · 522 bp chr2 IGKJ2 (-) ENST00000390241 · Ensembl canonical 88,861,525 breakpoint 88,861,525 88,861,563 1 exons · 38 bp
Canonical transcripts shown in genomic order on chr2 (lower-coordinate gene on the left). Each gene is drawn at its own zoom level. Introns are compressed to 1% of their genomic length so the exons are easier to see — the pixel-space x-axis is therefore non-linear, but the labelled start and end coordinates of each transcript are exact. The gap shown between the two panels (when on the same chromosome) is the actual distance between gene bodies. Transcript IDs are MANE Select where available, else Ensembl_canonical, else the longest protein-coding transcript.

Lung metastasis

Reportable 301 fragments (1 split, 0 discordant) · IGKJ2 exon 1 → IGKC exon 1

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