🌡️ Tumor expression vs normal tissue (GTEx)

How to use: on the Tumor vs GTEx tab, toggle the GTEx y-axis between the max or mean across 68 tissues, or percentile — what fraction of the ~19,800 GTEx normal samples each tumor sample exceeds for that gene (genes near 100% are over-expressed relative to essentially all normal tissue). Search a gene or click any point to open an information panel for it and see its distribution across every GTEx normal tissue and every PCAWG tumor type below, with vertical lines marking where the two tumor samples fall. Use the compartment chips to restrict the plots and the gene table (below the histograms) to a subcellular location — plasma-membrane genes are the most tractable immunotherapy targets. The gene table also reports a z-score — how many standard deviations each sample's log₂ expression sits above the GTEx (normal) or PCAWG (tumor) mean — which keeps discriminating genes even where the percentile saturates at 100%, and the full table downloads as TSV. The Assay Comparison tab plots the two tumors against each other to show how correlated the hand primary and lung metastasis are.