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NAIPP4::OCLNP1

High support

Canonical-transcript structure of the two partner genes, and the read-level evidence supporting the fusion in each tumor sample.

Known studies

No published studies in the Mitelman database describe the NAIPP4::OCLNP1 gene fusion. It may be novel, private to this case, or a technical artifact — absence from a curated database is not by itself evidence either way.

Canonical transcripts in genomic order spliced together in the fusion mRNA 9.7 kb apart chr5 OCLNP1 (-) ENST00000445744 · Ensembl canonical 71,093,192 breakpoint 71,074,225 71,093,193 5 exons · 19.0 kb chr5 NAIPP4 (-) ENST00000512908 · Ensembl canonical 71,104,744 breakpoint 71,102,898 71,128,753 9 exons · 25.9 kb
Canonical transcripts shown in genomic order on chr5 (lower-coordinate gene on the left). Each gene is drawn at its own zoom level. Introns are compressed to 1% of their genomic length so the exons are easier to see — the pixel-space x-axis is therefore non-linear, but the labelled start and end coordinates of each transcript are exact. The gap shown between the two panels (when on the same chromosome) is the actual distance between gene bodies. Transcript IDs are MANE Select where available, else Ensembl_canonical, else the longest protein-coding transcript.

Left hand (primary)

Reportable 54 fragments (30 split, 24 discordant) · NAIPP4 exon 8 → OCLNP1 exon 1
All 2 candidate breakpoints in this sample
Breakpoint (up)Breakpoint (down)TypeJunction TotalSplit RealignedDiscordant
chr5:71,104,744 chr5:71,093,192 DEL KNOWN/CANONICAL 54 30 0 24
chr5:71,108,661 chr5:71,093,192 DEL KNOWN/CANONICAL 16 6 3 7

Lung metastasis

Reportable 15 fragments (12 split, 1 discordant) · NAIPP4 exon 8 → OCLNP1 exon 1
All 2 candidate breakpoints in this sample
Breakpoint (up)Breakpoint (down)TypeJunction TotalSplit RealignedDiscordant
chr5:71,104,744 chr5:71,093,192 DEL KNOWN/CANONICAL 15 12 2 1
chr5:71,108,661 chr5:71,093,192 DEL KNOWN/CANONICAL 4 4 0 0

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