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SLC45A3::ELK4

Known partner

Canonical-transcript structure of the two partner genes, and the read-level evidence supporting the fusion in each tumor sample.

Known studies

Recorded in the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer in 4 publications (5 reported cases). Reported in: Acute myeloid leukemia, NOS; Adenocarcinoma; Nonneoplastic epithelial disorder/lesion.

Canonical transcripts in genomic order spliced together in the fusion mRNA 25.8 kb apart chr1 ELK4 (-) ENST00000357992 · Ensembl canonical 205,623,891 breakpoint 205,607,943 205,632,011 5 exons · 24.1 kb chr1 SLC45A3 (-) ENST00000367145 · Ensembl canonical 205,661,861 breakpoint 205,657,851 205,680,509 5 exons · 22.7 kb
Canonical transcripts shown in genomic order on chr1 (lower-coordinate gene on the left). Each gene is drawn at its own zoom level. Introns are compressed to 1% of their genomic length so the exons are easier to see — the pixel-space x-axis is therefore non-linear, but the labelled start and end coordinates of each transcript are exact. The gap shown between the two panels (when on the same chromosome) is the actual distance between gene bodies. Transcript IDs are MANE Select where available, else Ensembl_canonical, else the longest protein-coding transcript.

Left hand (primary)

Reportable 7 fragments (4 split, 3 discordant) · SLC45A3 exon 4 → ELK4 exon 2
All 2 candidate breakpoints in this sample
Breakpoint (up)Breakpoint (down)TypeJunction TotalSplit RealignedDiscordant
chr1:205,661,861 chr1:205,623,891 DEL KNOWN/KNOWN 7 4 0 3
chr1:205,680,394 chr1:205,623,891 DEL KNOWN/KNOWN 1 1 0 0

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