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TRAJ23::TRAC

High support

Canonical-transcript structure of the two partner genes, and the read-level evidence supporting the fusion in each tumor sample.

Known studies

No published studies in the Mitelman database describe the TRAJ23::TRAC gene fusion. It may be novel, private to this case, or a technical artifact — absence from a curated database is not by itself evidence either way.

Canonical transcripts in genomic order spliced together in the fusion mRNA 27.0 kb apart chr14 TRAJ23 (+) ENST00000390514 · Ensembl canonical 22,520,478 breakpoint 22,520,416 22,520,478 1 exons · 62 bp chr14 TRAC (+) ENST00000611116 · Ensembl canonical 22,547,506 breakpoint 22,547,506 22,552,156 4 exons · 4.7 kb
Canonical transcripts shown in genomic order on chr14 (lower-coordinate gene on the left). Each gene is drawn at its own zoom level. Introns are compressed to 1% of their genomic length so the exons are easier to see — the pixel-space x-axis is therefore non-linear, but the labelled start and end coordinates of each transcript are exact. The gap shown between the two panels (when on the same chromosome) is the actual distance between gene bodies. Transcript IDs are MANE Select where available, else Ensembl_canonical, else the longest protein-coding transcript.

Left hand (primary)

Reportable 84 fragments (70 split, 10 discordant) · TRAJ23 exon 1 → TRAC exon 1
All 2 candidate breakpoints in this sample
Breakpoint (up)Breakpoint (down)TypeJunction TotalSplit RealignedDiscordant
chr14:22,520,478 chr14:22,547,506 DEL KNOWN/KNOWN 84 70 4 10
chr14:22,520,475 chr14:22,547,510 DEL UNKNOWN/UNKNOWN 11 1 0 10

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