← All fusions

TRDJ1::TRDC

High support

Canonical-transcript structure of the two partner genes, and the read-level evidence supporting the fusion in each tumor sample.

Known studies

No published studies in the Mitelman database describe the TRDJ1::TRDC gene fusion. It may be novel, private to this case, or a technical artifact — absence from a curated database is not by itself evidence either way.

Canonical transcripts in genomic order spliced together in the fusion mRNA 12.8 kb apart chr14 TRDJ1 (+) ENST00000390473 · Ensembl canonical 22,450,139 breakpoint 22,450,089 22,450,139 1 exons · 50 bp chr14 TRDC (+) ENST00000390477 · Ensembl canonical 22,462,932 breakpoint 22,462,932 22,465,787 4 exons · 2.9 kb
Canonical transcripts shown in genomic order on chr14 (lower-coordinate gene on the left). Each gene is drawn at its own zoom level. Introns are compressed to 1% of their genomic length so the exons are easier to see — the pixel-space x-axis is therefore non-linear, but the labelled start and end coordinates of each transcript are exact. The gap shown between the two panels (when on the same chromosome) is the actual distance between gene bodies. Transcript IDs are MANE Select where available, else Ensembl_canonical, else the longest protein-coding transcript.

Left hand (primary)

Reportable 386 fragments (275 split, 96 discordant) · TRDJ1 exon 1 → TRDC exon 1
All 3 candidate breakpoints in this sample
Breakpoint (up)Breakpoint (down)TypeJunction TotalSplit RealignedDiscordant
chr14:22,450,139 chr14:22,462,932 DEL KNOWN/KNOWN 386 275 15 96
chr14:22,450,139 chr14:22,462,936 DEL KNOWN/CANONICAL 84 1 0 83
chr14:22,450,139 chr14:22,463,089 DEL KNOWN/CANONICAL 17 3 0 14

Lung metastasis

Reportable 4 fragments (4 split, 0 discordant) · TRDJ1 exon 1 → TRDC exon 1

Contact Us

Please contact us with any questions or comments.